Cold Spring Harbor Lab.
DNA replication and human disease.
In a volume dedicated to a pioneer in the study of DNA replication in eukaryotic (nucleated) cells, DePamphilis (National Institute of Child Health and Human Development, Bethesda, MD) introduces 36 chapters by international scientists working to understand how such cells replicate and repair their genomes. They review replication processes and current thinking about the relationship between DNA replication, disease, and targeted therapeutics. Appendices include DNA replication maps, an analysis of the evolutionary history of proteins challenging existing replication models, and summary tables of diseases caused by replication and repair defects and drugs to repair them. A companion website offers electronic versions of the book's figures. This is the update of DNA Replication in Eukaryotic Cells (1996). (Annotation ©2006 Book News Inc. Portland, OR)
Pandora's baby; how the first test tube babies sparked the reproductive revolution.
Henig, author of The Monk in the Garden: The Lost and Found Genius of Gregor Mendel, chronicles the early days of in vitro fertilization (IVF) and the ethical and legal battles surrounding it in the 1970's. The book was named one of the Best Books of 2004 by Library Journal and won the Outstanding Book Award for General Nonfiction from the American Society of Journalists and Authors in 2005. (Annotation ©2006 Book News Inc. Portland, OR)
Times of triumph, times of doubt; science and the battle for public trust.
Drawing on his elementary biology course for non-science majors, Carlson (emeritus, Stony Brook U., New York) explores good intentions, more specifically good intentions in science that lead to bad outcomes. He delves into the motivations of those involved, believing that an ethical analysis as well as a historical analysis is necessary to understand how people thought, what values they held, and the limitations of knowledge when they did their work (Annotation ©2006 Book News Inc. Portland, OR)